Direct moxibustion may be able to improve symptoms of fatigue, according to the results of a small study carried out in the US. Eleven female volunteers aged 25 to 60 years, all of whom were diagnosed with fatigue due to Spleen qi and yang deficiency, had three to five moxa cones burned at 11 acupuncture points once per week for eight weeks. Symptomatic improvement was seen after treatment on the SF-36 Energy/Fatigue Scale, SF-36 Social Function Scale and Flinders Fatigue Scale. Heart rate variability data also showed improvement in three of four participants. (Direct moxibustion to treat spleen qi and yang deficiency fatigue: a pilot study. J Acupunct Meridian Stud. 2014 Apr;7(2):76-82).

http:/ /www.ncbi.nlm.nih.gov/pubmed / 24745866

Qigong can reduce symptoms of fatigue and depression in patients with chronic fatigue syndrome (CFS)-like illness, a Hong Kong study has found. One hundred and thirty-seven participants who met the diagnostic criteria for CFS-like illness were randomly assigned to either an intervention group or a waitlist control group.  Participants in the intervention group received 10 sessions of qigong training twice a week for five consecutive weeks, followed by home-based practice for 12 weeks. At the end of the training period, the results showed that total fatigue score, physical fatigue score and depression score were significantly improved and mental fatigue score was marginally significantly improved in the qigong group compared to controls. Anxiety score was not significantly improved in the qigong group. (Effects of qigong exercise on fatigue, anxiety, and depressive symptoms of patients with chronic fatigue syndrome-like illness: a randomized controlled trial. Evid Based Complement Alternat Med. 2013;2013:485341).

A small, uncontrolled UK pilot study has found evidence of benefit for qigong in treating chronic fatigue. Eighteen women were taught a qigong routine during weekly classes over six months, and asked to practise it daily for 15 minutes. Participants completed a medical questionnaire and a sleep diary during the two-week baseline control period, and at three and six months following the start of the trial. The qigong intervention resulted in significant changes in scores related to sleep, vitality, social activity, pain, mobility and mental attitude after three and six months. (Qigong ameliorates symptoms of chronic fatigue: a pilot uncontrolled study. Evid Based Complement Alternat Med. 2009 Jun;6(2):265-70).

A British pilot study suggests that qigong can be used to manage the symptoms of chronic fatigue. Eighteen female participants were recruited, taught a qigong routine during weekly classes over six months, and asked to practise it daily for 15 minutes. Participants completed a questionnaire measuring health-related quality of life and a sleep diary during a two-week baseline control period, and at three and six months following the start of the trial. The qigong intervention resulted in significant changes in sleep rate score and in the subscales of the questionnaire related to vitality, sleep problems, social activity, health distress and psychological well-being; and the improvements were maintained at three and six months.  (Qigong Ameliorates Symptoms of Chronic Fatigue: A Pilot Uncontrolled Study. eCAM. 2008 Jul 15; doi:10.1093/ecam/nem088).