American researchers have found that acupuncture can offer significant improvements over usual care for treating chemotherapy-induced peripheral neuropathy (CIPN).  In a pilot randomised trial, they compared the effect of eight weeks of real versus sham acupuncture or usual care in 75 patients with CIPN.  The real acupuncture group received ear acupuncture at Shen Men, Point Zero, and a third electro dermally active ear point, along with needling at bilateral body points Hegu L.I.-4, Neiguan P-6, Houxi SI-3, Taichong LIV-3, Diwuhui GB-42, Fenglong ST-40, and Bafeng M-LE-8.  Electrical stimulation was also applied bilaterally from Taichong Liv-3 to Diwuhui GB-42.  The sham acupuncture group received a non-insertion procedure at non-acupoints.  Compared with usual care, pain, tingling and numbness significantly decreased in the real acupuncture group at week 8.  From baseline to week 8, the mean reduction in CIPN pain was greatest in the real acupuncture group (-1.75), followed by sham acupuncture (-0.91), with least reduction in the usual care group (-0.19).  At 12-week follow-up, real acupuncture maintained a mean reduction in pain of -1.74 from baseline, while sham treatment showed a reduction of -0.34. (Effect of Acupuncture vs Sham Procedure on Chemotherapy-Induced Peripheral Neuropathy Symptoms: A Randomized Clinical Trial JAMA Netw Open. 2020 Mar 2;3(3):e200681).