A combination of dense cranial electro-acupuncture stimulation plus body acupuncture (DCEAS+BA) can provide an effective rehabilitation therapy for neuropsychiatric sequelae of stroke. Chinese researchers randomised 91 stroke patients with post-stroke depression (PS) to either DCEAS+BA, or minimal acupuncture stimulation (MAS) for three sessions per week over eight consecutive weeks. For DCEAS+BA, six pairs of frontal acupoints received electrical stimulation (2Hz for 30 minutes at Baihui DU-20 and Yintang M-HN-3, left Sishencong M-HN-1 and Toulinqi GB-15, right Sishencong M-HN-1 and Toulinqi GB15, bilateral Shuaigu GB-8, bilateral Taiyang M-HN-9, and bilateral Touwei ST-8), and 15 body acupoints received manual stimulation (Guanyuan REN-4 and Shuigou DU-26, plus bilateral Shenmen HE-7, Hegu L.I.-4, Quchi L.I.-11, Zusanli ST-36, Fenglong ST-40 and Sanyinjiao SP-6). For MAS, six acupoints were stimulated (bilateral Shousanli L.I.-10 and Fuyang BL-59, with electrical stimulation at bilateral Tongtian GB-17). The DCEAS+BS treatment produced strikingly greater reduction of depression scores compared with MAS. The DCEAS+BA group also had a markedly higher clinical response rate, although the remission rate was not significantly different. Furthermore, the DCEAS+BA-treated patients showed considerably better outcomes related to cognitive performance, as well as improvements in functional disability associated with daily self-caring activities. (Assessor – and participant-blinded, randomized controlled trial of dense cranial electroacupuncture stimulation plus body acupuncture for neuropsychiatric sequelae of stroke. Psychiatry Clin Neurosci.2019 Nov 20. doi:10.1111/pcn.12959).