Indirect moxibustion using ginger combined with acupuncture can be a safe and effective way to relieve symptoms of chronic fatigue syndrome (CFS), and its effects after an eight-week treatment last for at least 12 weeks. Two hundred and ninety CFS patients were recruited by Chinese investigators and randomly allocated to group A (ginger-indirect moxibustion plus acupuncture) or group B (acupuncture alone). The treatment period lasted eight weeks, with three treatment sessions per week, and a follow-up period of 12 weeks. Acupuncture was applied at Baihui DU-20, Qihai REN-6, Zusanli ST-36, Taixi KID-3, Ganshu BL-18, Pishu BL-20, and Shenshu BL-23, with Sishencong M-HN-1 added for sleep or memory problems, and Neiguan P-6 and Sanyinjiao SP-6 added if patients suffered from digestive issues. Moxibustion was applied to the Governing and Bladder channels using a moxa box over ginger after needles had been removed. Both groups showed gradual improvement in fatigue and psychological scores over the treatment period, and these effects were maintained at 12-week follow up. Comparing groups, significantly greater changes were seen in group A in terms of fatigue scores after four weeks of treatment, and in psychological health scores after two weeks of treatment, suggesting an additional benefit of ginger indirect moxibustion over that of acupuncture alone.

Ginger-indirect moxibustion plus acupuncture versus acupuncture alone for chronic fatigue syndrome: a randomised controlled trial. J Tradit Chin Med. 2022 Apr;42(2):242-249.