Six-weeks of treatment with moxibustion seems to improve physical and mental quality of life in patients with chronic knee osteoarthritis (KOA). Chinese investigators randomly allocated 150 patients with KOA to either a true moxibustion group (n=77) or a sham moxibustion group (n=73), who received treatment three times a week for six weeks. Participants in the true moxibustion group experienced significantly greater improvement in general health scores than the sham group at weeks 6 and 12. Participants in the true moxibustion group also experienced statistically significantly greater improvement in vitality scores than the sham group at week 12. (Effectiveness of moxibustion treatment in quality of life in patients with knee osteoarthritis: a randomized, double-blinded, placebo-controlled trial. Evid Based Complement Alternat Med. 21)15;2015:569523. Epub 2015 Jan 21).