Tai chi is an effective intervention that can be delivered under pandemic conditions to improve mental and physical function in older adults. Thirty participants aged 60-78 were randomised to either a control group or a tai chi group for a 10-week period. The tai chi group received two eight-form tai chi classes of 60 minutes duration per week. Ten weeks of tai chi was found to improve cognition, measured in terms of visuospatial processing, inhibitory control and mental switching, and learning of fast and accurate reaching movements. Tai chi practice was associated with decreases in perceived stress, however no correlating objective change in autonomic nervous system activity was observed. Decreases in depressive symptoms and increased brain-derived neurotrophic factor levels were also observed and significantly correlated with cognitive scores for mental switching. (Tai chi improves psychoemotional state, cognition, and motor learning in older adults during the COVID-19 pandemic. Exp Gerontol. 2021 Jul 15:150:111363).